Research projects
-1-
Regulation and organization of mitochondrial gene expression
We are intrigued by the molecular mechanisms, by which mitochondrial gene expression is regulated. This is particularly important when cells need to produce more respiratory chain complexes, for example due to changed environmental conditions.
-2-
Mitochondrial protein homeostasis

Mitochondrial proteins can also be misfolded and then need to be repaired or turned over. How this works, and which roles mitochondrial gene expression plays for mitochondrial or cellular protein homeostasis, is an exciting area of our research.
-3-
Structural analyses of complexes we like

Single particle cryo electron microscopy has revolutionized modern life sciences. We determine with this technique the three dimensional structure of protein complexes implicated in the processes we study.
Our methods
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